What is the METADOL 100 MG Capsule?

Metadol 100 mg is a capsule formulation containing methadone hydrochloride, an opioid medication used primarily for pain management and as part of drug addiction detoxification and maintenance programs.

What Conditions Does METADOL 100 MG Capsule Treat?

Opioid Dependence:

It is commonly prescribed as part of a comprehensive treatment program for individuals who are dependent on opioids, such as heroin or prescription painkillers. Methadone helps reduce withdrawal symptoms and cravings, facilitating a smoother transition away from opioid use.

Chronic Pain:

Methadone is also used to manage severe chronic pain, particularly when other pain medications are ineffective. Due to its long-acting properties, it can provide extended relief from pain.

How does the METADOL 100 MG Capsule work?

Methadone, the active ingredient in Metadol, works by binding to opioid receptors in the brain and spinal cord. This action blocks the transmission of pain signals and alters the brain’s perception of pain. In addiction treatment, methadone helps reduce withdrawal symptoms and cravings associated with opioid dependence, allowing for a more gradual detoxification process.

How should I take the METADOL 100 MG Capsule?

Administration:

Take the capsule orally, as prescribed by your healthcare provider.

Dosage:

The dosage is individualised based on the condition being treated, the severity of the pain or dependency, and the patient's response to the medication.

Timing:

Follow the prescribed schedule rigorously; do not take more or less than advised. If taken for pain, it is usually given at regular intervals. For opioid dependence, it may be given once daily.

METADOL 100 MG Capsule Pros & Cons

Pros:

Effective in managing severe, chronic pain.
Helps in opioid addiction treatment by reducing withdrawal symptoms and cravings.
Long-acting, which can provide sustained relief and stability.

Cons:

Potential for addiction and abuse.
Can cause significant side effects and health risks, particularly with misuse.
Requires careful medical supervision.

What are the potential side effects of METADOL 100 MG Capsule?

Common Side Effects:

Nausea and vomiting
Constipation
Dizziness
Sweating
Dry mouth

Less Common Side Effects:

Headache
Weight gain
Fluid retention
Decreased libido

Serious Side Effects:

Respiratory depression (slow or shallow breathing)
Severe hypotension (low blood pressure)
Cardiac arrhythmias (irregular heartbeats)
Severe allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing)
Seizures

METADOL 100 MG Capsule: Precautions And Warnings

Addiction Risk: High potential for addiction, misuse, and abuse.
Respiratory Depression: Can cause severe breathing problems, especially during the initial stages of treatment.
Heart Issues: Risk of prolonged QT interval, which can lead to serious heart rhythm problems.
Interactions: May interact with other medications, including other opioids, benzodiazepines, and certain antidepressants.
Pregnancy and Breastfeeding: Should be used with caution; can affect the fetus and is excreted in breast milk.
Alcohol: Avoid alcohol consumption as it can increase the risk of serious side effects.

METADOL 100 MG Capsule: Dosage, Overdose, Missed Dose

Dosage:

Individualized based on medical condition and response to treatment.
For pain: Typically starts at a lower dose and adjusted as needed.
For addiction: Initial doses are carefully determined to avoid overdose, with gradual adjustments.

Overdose:

Symptoms include extreme drowsiness, slow or difficult breathing, muscle weakness, cold or clammy skin, fainting, or coma.
Immediate medical attention is required. Call emergency services or go to the nearest hospital.

Missed Dose:

Take the missed dose as soon as you remember.
If it is close to the time of your next dose, skip the missed dose and resume your regular dosing schedule.
Do not double the dose to catch up.

Contradiction of METADOL 100 MG Capsule

Known Hypersensitivity:

Should not be used by individuals allergic to methadone or any other ingredient in the capsule.

Respiratory Issues:

Not suitable for patients with significant respiratory depression or acute asthma.

Paralytic Ileus:

Should not be used in cases of gastrointestinal obstruction.

Concurrent MAOI Use:

Should not be used with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping such treatment.

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Reference

https://pdf.hres.ca/dpd_pm/00034071.PDF